Liver is the largest internal organ in the body. It is produces over 1000 enzymes and performs over 500 functions. In the case of liver failure, the liver transplantation becomes necessary. The liver is the only organ of the body that can grow to full within few weeks of transplantation. Only 25 % of the transplanted liver can grow into full liver after weeks of transplantation. But in case of failure of liver to function, the liver transplantation becomes necessary as there is no device or machine that can replace liver in the human body.
Diseases that can lead to liver transplantation –
Acute liver failure can result from chronic liver hepatitis, which can be hepatitis B, C and D, which can cause inflammation and permanent damage to the liver. Other disease is autoimmune hepatitis in which the body‘s immune system does not function properly and leads to destruction of liver tissue. The deposition of fat in the liver can also damages the liver
The acute liver failure can happen when the liver has suffered massive injury that has rendered it ineffective to perform the normal functions. Overdose of medicines, viral infection, eating some poisonous substances such as mushroom can also lead to liver failure.
Chronic liver failure can also damage the liver permanently. Though, liver has ability to regenerate itself, but repeated injuries or repair over many years may render it incapable of regeneration. The end stage, when liver is not able to regenerate itself is called cirrhoses. The cirrhosis of liver is the stage, when transplantation of the liver becomes necessary. Then there are some genetic diseases and failure of liver due to heavy consumption of alcohol.
Liver transplantation Liver Transplant in Delhi operation involves removal and preparation of the livers from donor and patient. The implantation of the liver must be done carefully, because liver has several connections, all of which must be reconnected for receiving blood and draining bile from liver. The structures that are connected are inferior vena cava, the hepatic artery, bile duct and portal vein. The exact method of connecting depends on the donor and recipient’s anatomy issues or in some cases the diseases of the recipient.
The success rate Liver Transplant Hospital in Delhi of liver transplantation rate is very high. In some cases about 1-5 %, the newly transplanted liver may not function properly or normally. If the transplantation is not successful, then the patient may require second transplantation immediately.