Process of liver transplant and types of liver transplants

images (49)

Liver transplant begins with the referral to transplant center by the doctor. The patient is examined by the team of doctors to determine whether the patient is in need for transplant. The examination is done by testing blood, urine, physical examination, x rays, imaging tests and tests are also conducted to test the function of heart, kidneys and lungs.

h9991470_005

The liver transplant is Liver Transplant in Delhi complex and can last up to 12 hours. The patient receiving the liver is given general anesthesia.  The intravenous lines are inserted to give medicine and fluid and catheter drain the urine from bladder.  An incision is done at the upper abdomen and surgeon access the liver. The liver, which is to be removed from the patient, is detached from blood vessels, and bile duct.

The donor liver is then put in the same place, where the damaged liver is taken from. It is also noted whether the donor liver is producing the bile. The blood vessels and bile duct of the recipient is attached with the donor liver. If the bile duct of the recipient cannot be attached with the bile duct of the donor liver, then the bile duct of the donor is drained into the small intestine loop.

After the surgery, the patient is shifted to the intensive care unit. After some stabilization, the breathing tube for general anesthesia is taken out and patient is send to general ward. The patient has to stay in the hospital for couple of weeks.

The person giving segment of the liver also has to stay in hospital after surgery for at least one week. The donor also has to go through surgery, in which segment of the healthy liver is taken out.

Types of liver transplant –

unnamed

There are three ways to perform the liver transplant. One is deceased organ donation from the person who is already dead. Other is donation from the person who is living. The segment of the living healthy Liver Transplant Hospital in Delhi  liver is taken out from the living person. The segment in both the donor and receipt can grown into normal size .Third is split donation, here the segment from the deceased person‘s liver is given to two persons. The segments can grow into normal sizes in two different persons.

The person who receives the liver can return to the normal life after some months. The patient has to take medicine to stop the body from rejecting the new liver. This medication, immunosuppressant has to be taken for the rest of the life by the person who received liver.

Reasons that lead to liver transplantations

Liver Transplant Surgeon

Liver is the largest internal organ in the body. It is produces over 1000 enzymes and performs over 500 functions. In the case of liver failure, the liver transplantation becomes necessary. The liver is the only organ of the body that can grow to full within few weeks of transplantation.  Only 25 % of the transplanted liver can grow into full liver after weeks of transplantation.  But in case of failure of liver to function, the liver transplantation becomes necessary as there is no device or machine that can replace liver in the human body.

Diseases that can lead to liver transplantation –

Acute liver failure can result from chronic liver hepatitis, which can be hepatitis B, C and D, which can cause inflammation and permanent damage to the liver.  Other disease is autoimmune hepatitis in which the body‘s immune system does not function properly and leads to destruction of liver tissue. The deposition of fat in the liver can also damages the liver

The acute liver failure can happen when the liver has suffered massive injury that has rendered it ineffective to perform the normal functions. Overdose of medicines, viral infection, eating some poisonous substances such as mushroom can also lead to liver failure.

h9991470_005

Chronic liver failure can also damage the liver permanently. Though, liver has ability to regenerate itself, but repeated injuries or repair over many years may render it incapable of regeneration. The end stage, when liver is not able to regenerate itself is called cirrhoses. The cirrhosis of liver is the stage, when transplantation of the liver becomes necessary. Then there are some genetic diseases and failure of liver due to heavy consumption of alcohol.

Liver transplantation Liver Transplant in Delhi operation involves removal and preparation of the livers from donor and patient. The implantation of the liver must be done carefully, because liver has several connections, all of which must be reconnected for receiving blood and draining bile from liver. The structures that are connected are inferior vena cava, the hepatic artery, bile duct and portal vein. The exact method of connecting depends on the donor and recipient’s anatomy issues or in some cases the diseases of the recipient.

Liver Transplant Surgeon

The success rate Liver Transplant Hospital in Delhi of liver transplantation rate is very high. In some cases about 1-5 %, the newly transplanted liver may not function properly or normally. If the transplantation is not successful, then the patient may require second transplantation immediately.

Treatment of the Liver or Hepatic Disease

Liver Transplant Surgeon

Medications and surgical procedures used in the treatment of the chronic and acute liver diseases are discussed in this blog. Acute and chronic liver diseases can be treated through medication and surgical procedures.

For the purpose of effective treatment of the liver diseases such as hepatitis C, the use of anti viral medication is prescribed by doctors. Other liver diseases can be managed and treated by using medication that slows down the liver disease progression. For the purpose of treatment of autoimmune hepatitis, the use of steroid based drugs is prescribed by doctors in Delhi.

Hemochromatosis is another liver disease within the iron overloads conditions, can be treated by removal of a quantity of blood from the vein. The method of treatment of Hemochromatosis is known as venesection. Drugs, which bind to the copper and allowing it to pass from the body of the patients through urine, can be used to treat Wilsons’ disease, which is condition where excess copper built up in the body.

Cholestatic liver disease can be treated by using ursodeoxycholic acid, under the supervision of qualified and experienced doctors. Hepatic transplantation is used for the purpose of replacement of diseased liver with healthy liver through the liver transplantation surgical procedures in India.

Liver diseases that cannot be treated through medications and requires immediate liver transplant for ensuring normal functioning of the liver, are known as chronic liver diseases. Corticosteroids and interferon that are combined with antiviral drugs and bile acids can be used for the purpose of effective treatment of different chronic liver diseases and complications.

Supportive therapy can be used for the purpose of treatment of chronic liver diseases. In last stages of chronic liver diseases, the only treatment is through quick and effective liver transplantation.

Liver Transplant Surgeon

Typically three Liver Transplant Surgeon and two anesthesiologists are involved in carrying out the liver transplantation procedures for treatment of chronic liver complications.

By using modern machinery and most recent technology, the surgeons ensure high effectiveness. In addition to this, four supporting nurses are required for the purpose of providing Liver Transplant in Delhi in the most effective manner.

Liver Transplant in Delhi

Typically the surgical procedures require 4 to 18 hours depending on the outcome of the surgical procedures. In addition to this, chronic liver diseases can be treated through different herbal remedies. The evidence of the herbal remedies for the purpose of treatment of chronic liver diseases is not conclusive.

Causes and Treatments of Acute Hepatic Insufficiency and Chronic Hepatic Insufficiency

Inability of the liver to perform its functions both metabolic and synthetic is known as hepatic insufficiency. The hepatic insufficiency can be classified into acute hepatic insufficiency and chronic hepatic insufficiency. Two types of hepatic insufficiency are discussed in this blog.

Acute Hepatic Insufficiency

Loss of function of 80–90% of liver cells is associated with acute hepatic insufficiency. Physical exam, laboratory findings and patient history are used for the purpose of effective diagnosis of acute liver failure.

One of the common causes of the acute hepatic insufficiency is acetaminophen overdose. Other causes of the acute hepatic insufficiency are idiosyncratic reaction to medication. Furthermore, the acute hepatic insufficiency can be caused due to excessive alcohol consumption.  Viral hepatitis, such as hepatitis A or B, can cause acute hepatic insufficiency.

liver-transplant

As per the recent studies, it was reported that the acute hepatic insufficiency can be caused by acute fatty liver of pregnancy. Furthermore, the acute hepatic insufficiency can be caused by idiopathic. Furthermore, Wilson’s disease can also cause acute hepatic insufficiency.

Patients suffering from the acute hepatic insufficiency are managed in the intense care unit as they often involve in the rapid deterioration of mental status. As acute hepatic insufficiency is associated with possibility of rapid progression, hence it is always critical for make early consultation with excellent transportation facility.

Low systemic vascular resistance and increased cardiac output are associated with acute hepatic insufficiency. Catheterization of pulmonary artery of should be done in cases of cardiovascular complications. Acute Hepatic insufficiencies are associated with pulmonary edema and pulmonary infections.

As per the recent study conducted, it was reported that the instant survival rate of the patient suffering from the acute hepatic insufficiency is now around 40% at some of the well-known and reputed hospitals in Delhi.

Acute hepatic insufficiency patients with grade I-II encephalopathy should be transferred to transplantation facilities and lists them for Liver Transplant in Delhi.

Chronic Hepatic Insufficiency

Progressive destruction and regeneration of the liver parenchyma is known as chronic liver disease, which results in cirrhosis and fibrosis.

Hepatitis B and Hepatitis C are considered to important factors causing chronic hepatic insufficiency. Moreover, Alcoholic liver disease can cause chronic hepatic insufficiency.

Non-alcoholic fatty liver disease and Haemochromatosis can also cause the chronic hepatic insufficiency. Right heart failure and autoimmune diseases can also cause chronic hepatic insufficiency.

Based on the cause of the chronic hepatic insufficiency, the treatment can be carried out through corticosteroids and interferon. Other medications used for the treatment of chronic hepatic insufficiency are antiviral and bile acids.

Apart from medication, the patients might require liver transplantation in cases of last stage of chronic hepatic insufficiency.

Liver Transplant Hospital in Delhi often indicates patients suffering from the acute hepatic insufficiency with liver transplantation with success rate of 56–90%. Better survival rates were attained through with better critical care and trend towards more benign causes, in addition to the liver transplantation procedures.

Different Types of Organ Transplants & Donors and Benefits of Liver Transplantations in Delhi

Liver Transplant Surgeon

For the purpose of replacing the damage or absent organ, the organ from the donor body is effectively moved to the receipt body.  In accordance to the conditions of the patients, the organs that can be transplanted are kidneys, liver, and lungs. Moreover, the heart, pancreas and thymus can also be transplanted for the purpose of replacing damage or absent organ effectively.

Various types of Transplant Procedures

Different types of transplant used across the world are Autograft, Allograft & Allotransplantation. In addition to this, Xenograft and xenotransplantation can also be used for the purpose of effective transplantation.  The Split transplants, and Domino transplants, are also popular types of transplant procedures used across the world. ABO-incompatible transplants and Transplantation in obese individuals are used across the world, for the purpose of ensuring optimum functionality of the body.

Different Types of Donor for the Organ Transplant

The donor of the organ transplant can be both living and deceased with circulatory death or brain death.  Only renewable organs such as blood and skin can be donated by the living donors. Besides this, the living donors can donate part of organ such as kidney or liver that can work effectively in their absence.  Living donors often donate their organs to their friendly and family, in fear to losing them due to lack of donor or long waiting list of getting the donated body parts. The body of brain dead patients are kept in ventilators can donate most of their body parts for the purpose of effective transplant processes.

Liver Transplants in Delhi 

In the cases of acute liver failure, the doctors recommend only viable options as liver transplantation as soon as possible.  Besides this, the liver transplantation is recommended in cases of end-stage liver disease. One of the major complications associated with liver or organ transplantation is graft rejection, which can be of three types in cases of liver transplant.  The three types of graft rejection common in liver transplant are hyperacute rejection, acute rejection and chronic rejection.  For avoiding or preventing the graft rejection, the Liver Transplant Surgeon makes use of high dose of immunosuppressive drugs.

Liver Transplant Surgeon

Supervised doses of Corticosteroids with a calcineurin inhibitor are often used as immunosuppressive drug in major cases of liver transplantation.  As per recent studies conducted, it was reported that only 10% to 20% cases of failure with new liver was found during the studies conducted.

A team of experienced three liver transplant surgeons, two anesthesiologists and four nurses are required for conducting liver transplant surgical procedures that can effectively lasts for 5 to 9 hours, in accordance to the outcome of the surgical procedures.

The replacement of diseased liver with healthy liver through systematically executed Liver Transplant in Delhi can save the life of patients suffering from liver failure or irreversible liver damage. One of the most popular techniques used for the purpose of systematic liver transplant is orthotopic transplantation.

Liver Transplant in Delhi

More than 725 liver transplantation surgeries performed by Dr. Naimish N. Mehta

Liver Transplant Surgeon

For management and treatment of cirrhosis, it is advised and recommended by doctors to undergo liver transplantation under experienced surgeons or liver transplant consultants.  By supervising and performing more than 725 liver transplantations, Dr. Naimish N. Mehta has attained respectable positions as one of the liver transplant consultants in Delhi.

Liver transplant consultants render consultancy for liver transplantation in the case of liver damage caused due to cirrhosis. Years of experience and knowledge of liver transplantation, Dr. Naimish N. Mehta has performed more than 725 liver transplantations till date.

Talking about the indications for liver transplantation, Dr. Naimish N. Mehta said, “Liver transplantation is needed in cases of acute or fulminant liver failure, chronic liver disease, and extra hepatic biliary artesia. In addition to this, individuals need liver transplantations in complicated cases of malignancy, metabolic disorders, and polycystic liver disease”.  “93% success rate is usually associated with liver transplantation undergoing Living donor liver transplantation”, Dr. Naimish N. Mehta said talking about the success rate associated with liver transplantation with liver donor.

Liver Transplant in Delhi

“We reported lower number of biliary complications that are less than 5%. Success rate or survival rate associated with patients undergoing liver transplantations with liver cancer is more than 85%”, Dr. Naimish N. Mehta said, who is counted as the best Liver Transplant Surgeon in Delhi.  Latest technology and transplantation equipment are used for conducting liver transplantation under the supervision of qualified liver transplant consultants, in the most organized manner.

In-depth knowledge and experience of liver transplantation domain, has helped Dr. Naimish N. Mehta in performing more than 725 liver transplantations in Delhi. MBBS, MS, FACRSI, and FEBS, are some of the educational qualifications of Dr. Naimish N. Mehta. Certified for Multi-organ Retrieval surgery & Diploma in Liver Transplantation, Dr. Naimish N. Mehta holds expertise in liver transplantation procedures.  In addition to this, Dr. Naimish N. Mehta has done Fellowship in Liver Transplantation from United Kingdom (U.K), for upgrading his liver transplantation skills in organized manner. Both cadaveric and living donor liver transplants are performed by Dr. Naimish N. Mehta, by using cutting-edge equipment and technology. Liver Transplant in Delhi carried out by Dr. Naimish N. Mehta, is known for its high success rate of 93%. In addition to this, the cases of liver transplantation with liver cancer are associated with 85% success rate.  In compared to liver transplantation across the world, the number of biliary complications that is 5%.  Quick post operation recovery, less pain and optimum success rate, makes the liver transplantation procedures conducted by Dr. Naimish N. Mehta extremely appreciated and demands by individuals suffering from cirrhosis.

Company Details:-

Dr. Naimish N. Mehta,

HPB & Liver Transplant Surgeon,

No. 2222, Department of Surgical GI & Liver Transplant Unit I,

Sir Ganga Ram Hospital, New Delhi – 110060

Phone Number: 011-42252222 and 09811350626

Website: – http://www.livertransplant.co.in/

Email: – dr.nmehta@hotmail.com